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Extraction of a range of immunosuppressants from whole blood using ISOLUTE SLE+ prior to LC-MS/MS analysis

Resource type: 
Application note
Author(s): 
Biotage
Format: 
pdf
Date of creation: 
5 November 2017
Library code: 
11399

ISOLUTE SLE+ Supported Liquid Extraction plates offer an efficient alternative to traditional liquid-liquid extraction (LLE) for bioanalyticalsample preparation, providing high analyte recoveries, no emulsion formation and significantly reduced sample preparation.

This application note describes the extraction of sirolimus, tacrolimus, everolimus and cyclosporin A from whole blood samples using supported liquid extraction prior to LC-MS/MS analysis.