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Metal mitigation, extractables and regulatory perspectives

Resource type: 
Application note
Author(s): 
Biotage
Format: 
pdf
Date of creation: 
28 March 2019
Library code: 
12410

Metal scavengers were first investigated for inherent metals content by ICP analysis methods. Then, these scavengers were extracted in a range of common solvents in order to show extractable/leachable levels. Lastly, an example metal scavenging mitigation step is demonstrated, looking at the corresponding API mass yield, purity and also metals data.