Scavenging oxophilic metal complexes using PS-DEAM polymer-bound diethanolamine

PS-DEAM is a polystyrene-bound diethanolamine, which is a resin-bound equivalent of the tridentate (N, O, O) N-alkyldiethanolamine ligand. PS-DEAM is an effective scavenger for a variety of oxophilic organometallic and inorganic complexes. The resin can be used to quench reactions and remove metallic reagents, catalysts or byproducts, allowing the purified product to be isolated by filtration. Boronic acids are scavenged by PS-DEAM. This has been exploited in the purification of Suzuki reactions through the removal of excess boronic acid and coupling byproducts.

In this application note, oxophilic metal complexes were scavenged, including: boronic acids, titanium(IV) chloride, titanium(IV) isopropoxide and tin (IV) chloride.