Biotage ISOLUTE SLE+ Supported Liquid Extraction products

Achieving simplicity and success in sample preparation
(extract of Biotage 2017 analytical sample preparation catalog)
ISOLUTE® SLE+ Supported Liquid Extraction columns and plates are designed to provide stress free extraction of analytes from biological fluids, using a simple Load-Wait-Elute methodology. The supported liquid extraction (SLE) process is analogous to traditional liquid-liquid extraction (LLE) and utilizes the same water immiscible solvent systems for analyte extraction. Instead of shaking the two immiscible phases together, in SLE, the aqueous sample is immobilized on an inert support, and the organic phase flows through the support, eliminating problems such as emulsion formation and low analyte recoveries.
Typical ISOLUTE SLE+ procedure
Methods with high analyte recoveries, and clean, protein and phospholipid free extracts, are easy to develop and automation is simple. The correct ISOLUTE SLE+ product is selected simply based on the volume of sample to be extracted.