Rapid gravity separation of two phase systems using ISOLUTE phase separator columns and 96-well plates

Biotage ISOLUTE phase separators have been designed to rapidly separate chlorinated solvents from aqueous phases, under gravity. The phase separators are available in a comprehensive range of column sizes (3, 6, 15, 25, 70 and 150 mL) and also in 96-well plates (fixed well and the versatile ISOLUTE array formats). Unlike other phase separation devices, no vacuum or positive pressure is required – the separation is achieved under gravity. The phase separator is impervious to aqueous solvents, but allows the passage of water immiscible solvents of a higher density than water.

This chemistry data sheet describes the use of ISOLUTE phase separator columns and 96-well plates to separate aqueous solutions from chlorinated organic solvents.