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Extraction of acrylamide from coffee and potato chips using supported liquid extraction (SLE) prior to LC-MS/MS analysis

Resource type: 
Poster
Author(s): 
Biotage
Format: 
pdf
Date of creation: 
8 March 2018
Library code: 
11625

The supported liquid extraction (SLE) process is analogous to traditional liquid-liquid extraction (LLE) and utilizes the same water immiscible solvent systems for analyte extraction. Instead of shaking the two immiscible phases together, in SLE, the aqueous sample is immobilised on an inert support and the organic phase flows through the support, eliminating problems such as emulsion formation and low analyte recoveries.

This poster demonstrates a novel, sensitive, cost effective and rugged method for the analysis of acrylamide in coffee and potato chips (crisps) using supported liquid extraction prior to LC-MS/MS analysis. An extraction from coffee down to a concentration of 1 ng/mL and in potato chips to a level of 10 ng/g (ppb) is demonstrated.