Extraction of buprenorphine and norbuprenorphine from whole blood using ISOLUTE SLE+ Supported Liquid Extraction prior to LC-MS/MS analysis
Resource type:
Application note
Format:
pdf
Date of creation:
9 October 2017
Library code:
11297
ISOLUTE SLE+ Supported Liquid Extraction products offer an efficient alternative to traditional liquid-liquid extraction (LLE) for bioanalytical sample preparation, providing high analyte recoveries, no emulsion formation and significantly reduced sample preparation time.
This application note describes the extraction of buprenorphine and norbuprenorphine from whole blood using ISOLUTE SLE+ Supported Liquid Extraction prior to LC-MS/MS analysis. A fast extraction protocol for the qualitative and quantitative analysis of buprenorphine and norbuprenorphine extracted from whole blood matrix is described.
