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Biotage Extrahera sample preparation automation system
Extrahera is a powerful, user friendly automation system for Supported Liquid Extraction (SLE), Solid Phase Extraction (SPE), Phospholipid Depletion (PLD) and Protein Precipitation (PPT) based methods, in plate or column formats.

Extraction of NSAIDs from plasma using ISOLUTE SLE+
Automated sample preparation using the Biotage Extrahera was compared to an equivalent manual method utilizing a vacuum manifold. A significant reduction to the % RSD was measured when using the Extrahera compared to the manual processing approach.

Extraction of beta blockers from plasma using ISOLUTE SLE+
Automated sample preparation using the Biotage Extrahera was compared to an equivalent manual method utilizing a vacuum manifold.

Extraction of 25-OH vitamin D from plasma using ISOLUTE SLE+
Automated sample preparation using the Biotage Extrahera was compared to an equivalent manual method utilizing a vacuum manifold.

Evaluation of drugs of abuse extraction from whole blood using supported liquid extraction prior to GC/MS analysis
Supported liquid extraction allows for the simultaneous analysis of cross functional analytes in a single extraction protocol without forfeiting extract cleanliness.

Evaluation of novel automated sample preparation compared to manual processing in forensic toxicology
This poster compares the performance of manual processing to a novel automated sample preparation system prior to GC/MS or LC-MS/MS analysis.

Simultaneous extraction of catecholamine and metanephrines from urine prior to analysis using LC-MS/MS
This poster discusses the impact of optimization of various parts of the method development process to maximize assay performance while delivering a combined assay for the analysis of urinary catecholamines and metanephrines.

Evaluation of three beta-glucuronidase enzymes to determine the best hydrolysis conditions for urine samples in clinical toxicology and pain management
Red abalone (Kura Biotech), abalone (Campbell Scientific) and recombinant (IMCSzyme) beta-glucuronidase enzymes were evaluated to determine which provided the most complete hydrolysis of glucuronide metabolites without effecting the overall recovery of non-conjugated compounds.

Drugs of abuse with multivariate intermolecular properties analyzed by polymeric mixed-mode cation exchange
In this poster Biotage demonstrates that a large urine panel, comprised of 43 DOA’s, from multiple drug classes, can be simultaneously screened by mix-mode cation exchange despite their disparate intermolecular traits, by thoughtfully selecting appropriate organic wash and elution conditions that simultaneously enable sample isolation and detection along with minimizing sample matrix effects.

Biotage analytical sample preparation 2017
This catalog presents the extensive range of products for analytical sample preparation from Biotage.

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