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RapidTrace SPE workstation automated high throughput SPE extraction
RapidTrace SPE workstation is designed especially for the regulated pharmaceutical, clinical and forensic environment, RapidTrace is also a robust automated platform for quickly developing rugged, reliable SPE methods.

Cleaning and maintenance of Biotage RapidTrace workstation
Whichever matrix and reagents are running through the system, traces of these liquids will be left after use; proteins from plasma, precipitates from buffers or even particulates from oral fluid. Over time if the following cleaning schedule is not observed these contaminants could cause blockages leading to malfunctions and/or cross contamination.

Biotage RapidTrace+ automated SPE workstation
The RapidTrace+ is a robust automated platform for quickly developing rugged, reliable SPE methods in regulated pharmaceutical, clinical and forensic laboratories. The RapidTrace+ eliminates SPE bottlenecks so you can realize the full benefits of today’s powerful analytical instruments.

Automated solid phase extraction of organic compounds from marine sediments, soil and dust samples
The extraction and segregation of organic compounds from core samples taken from marine sediments is used to predict climate conditions, reconstruct sea temperatures and identify the type of vegetation from the C3 ( temperate climate) and C4 ( tropical climate) isotopic mass spectroscopy ratio analysis.

Automated SPE extraction of benzoylecgnonine from urine for confirmation by GC/MS
When analyzing human urine for drugs of abuse, one of the most common tests is for the cocaine metabolite Benzoylecgonine (BZE). A contract laboratory has automated this labor intensive procedure using the RapidTrace.

RapidTrace procedure for the automated fractionation of EPH in soil using ISOLUTE EPH SPE columns
This application note describes the operating conditions for the automated fractionation of EPH into aliphatic and PAH fractions using the ISOLUTE EPH column in conjunction with the caliper RapidTrace SPE automation system.

Method for the extraction of the cocaine metabolite, benzoylecgonine from urine using ISOLUTE HCX and RapidTrace
Cocaine is absorbed and metabolized extremely efficiently and rapidly through the liver which makes it difficult to detect in drugs of abuse testing. When screening for the presence of cocaine in urine it is more appropriate to test for the presence of the major metabolite of cocaine; benzoylecgonine.

Method for extraction of tricyclic antidepressants from whole blood using ISOLUTE HCX columns and RapidTrace
Cocaine is absorbed and metabolized extremely efficiently and rapidly through the liver which makes it difficult to detect in drugs of abuse testing. When screening for the presence of cocaine in urine it is more appropriate to test for the presence of the major metabolite of cocaine; benzoylecgonine.

Method for the extraction of basic drugs of abuse from biological fluids using ISOLUTE HCX & RapidTrace workstation
The typical range of drugs screened using this generic method are cocaine, D3-cocaine, benzoylegonine-TMS, D3-Benzoylegonine-TMS, amphetamine, D5-amphetamine, methamphetamine, codeine, morphine, amitriptyline HCL, nortriptyline HCL, imipramine HCL and desipramine HCL.

Method for the extraction of cyclosporine from whole blood using ISOLUTE SI columns and RapidTrace
workstation
Cyclosporine is an immunosuppressant drug most significantly used in post-operative organ transplants to reduce the chance of rejection of donor organs by decreasing the activity of the patient’s immune system. Subsequent to an organ transplant, patients are tested at regular intervals for the presence of very low levels of the compound.

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