Drugs of abuse extraction from oral fluid using supported liquid extraction (SLE) following collection with NeoSal prior to GC/MS analysis

Screening drugs of abuse can be complicated due to the wide variation of functional groups associated with different analyte classes. Most extraction techniques cannot extract all analytes using a single procedure without using non-optimal extraction protocols, resulting in compromised extract cleanliness. Supported liquid extraction allows for the simultaneous analysis of cross-functional analytes in a single extraction protocol without forfeiting extract cleanliness.

This poster demonstrates protocols for the determination of a range of drugs of abuse following collection with the NeoSal oral fluid device and GC/MS analysis. The drug suites included amphetamines and synthetic cathinones, barbiturates, benzodiazepines, cocaine, opiates, cannabinoids and synthetic cannabinoids.