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High-throughput CD spectral measurement for the evaluation of pH dependency of biomedicines
In this application note, JASCO demonstrates the use of the ASU-800 automated system to evaluate the pH dependency on the structure of human serum albumin (HSA).

High-resolution Circularly Polarized Luminescence (CPL) spectrum measurement of an europium complex
JASCO has developed a high sensitivity CPL spectrometer. By combining CPL with ECD, more structural information regarding chiral molecules can be obtained.

Change in the fluorescence anisotropy spectrum by the denaturation of α-lactalbumin by guanadinium hydrochloride
This application note describes the use of the Jasco J-1500 CD spectrometer to measure fluorescence anisotropy.

CD measurement of α-pinene gas in the vacuum-UV region
This application note demonstrates that spectra of gas samples can be obtained using the J-1500 CD spectrometer with high signal-to-noise in the vacuum UV region.

CD measurement of protein film samples in the vacuum UV region
Marker bands for specific secondary structures are most typically observed in the UV region below 260 nm and as far into the far-UV region as possible. It has been widely reported that CD measurements using synchroton radiation have been used to successfully measure spectra down to around 140 nm. As an alternative to synchrotron radiation, the J-1500 CD spectrometer has been improved for measurements in the vacuum UV region.

Measurement of the complex forming reaction of nickel sulfate and Rochelle salt probed by stopped-flow CD spectroscopy
Stopped-flow CD can be used to observe complex-forming reactions. Transition metal complexes typically exhibit absorption bands in the visible to near-infrared region of the spectrum and CD measurements can be used to probe structural changes occurring in this region.

Automated dissolution sampler
The Evolution 4300 is equipped with state-of-the-art electronics and utilizes highly reliable and accurate syringe pumps for sample collection. Accommodating up to two independent syringe pumps, both dual sampling and simultaneous dissolution methods make the Evolution 4300 the premier Dissolution sampler option.

In-situ UV fiber optic system for dissolution testing
The Distek Opt-Diss 410 UV fiber optic system for dissolution testing measures directly in the vessel, eliminating problematic filters, tubing and pumps used in conventional sampling.

Distek products overview
Distek is a leading manufacturer of laboratory testing instruments for the pharmaceutical and biotechnology industry for over 40 years, as well as an experienced provider of validation and qualification services.

Evaluation of antireflection film with using absolute reflectance measurement accessory
This application note proved that JASCO Automated absolute reflectance measurement accessory can be applied to the reflectance measurement with less than 0.1%.

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