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Gilson Pipetmax: flexible automated workflow for kinase selectivity profiling
Automation of the kinase selectivity profiling system with the Pipetmax, in conjunction with automated detection and data analysis methods, offers a streamlined workflow for single-point and dose-response evaluation of potential cancer therapies.

Gilson Pipetmax: automation of the Agencourt AMPure XP PCR purification system
This application note demonstrates a flexible and reliable automated procedure for next-generation sequencing (NGS) library cleanup. This script can process up to 96 samples in a single run, increasing throughput and providing consistency for a challenging procedure.

Gilson Pipetmax: automating 384-well qPCR plate preparation
In this application, the Pipetmax was used to automatically prepare 384-well qPCR plates in order to monitor PVY levels post infection.

Gilson Pipetmax: automated library prep for BRCA MASTR Dx diagnostic assay
The Gilson Pipetmax, a small, personal liquid handling system, performs all liquid handling steps for the BRCA MASTR Dx kit to create and purify libraries for next generation sequencing (NGS). The results show that using Pipetmax achieves consistent and reproducible results for the amplification, pooling, and cleanup of samples.

Optimization of qPCR master mix dispensing with Pipetmax by Gilson
In this application note, Gilson used the Pipetmax automated liquid handler to test whether the number of times a tip was pre-wet before transferring master mix affected qPCR performance.

Nextera XT DNA library preparation on Pipetmax by Gilson
In this application, Gilson compared sequencing results for E. coli whole genome sequencing libraries prepared with the Illumina Nextera XT kit, with liquid handling carried out either manually or automated with Pipetmax. The automated methods provided reproducible liquid handling, resulting in smaller standard deviations and lower variance between replicates.

Increased efficiency of the coomassie protein assay for protein content determination using simple automated liquid handling vs. manual procedures
In this application, the Gilson Pipetmax was used successfully to automate the 96-well coomassie protein assay, pipetting samples, standards, and reagents with comparable accuracy and consistency relative to manual results.

Gene expression signature in peripheral blood as a marker of parkinson’s disease
In this application by Gilson, five genes were selected based on the results of past global gene expression studies, and qPCR validation study was performed on samples taken from an independent subset of patients with PD and matched controls. The qPCR experiment was designed and prepared using the Pipetmax qPCR assistant software and the Pipetmax 268 automated pipetting instrument.

Gilson Pipetmax automation of the coomassie (bradford) protein assay using a multiple channel bench top
The bradford assay performed in this application was automated using the Pipetmax 268 bench top pipetting system. Absorbance of the coomassie dye bound to albumin protein was measured with the Vmax kinetic microplate reader. Results were compared with manual method performance using a combination of the Pipetman L single channel and Pipetman M multichannel pipettes.

Automating the Promega GoTaq PCR core system II reaction using the Gilson Pipetmax 268
In this application, the compact Pipetmax 268, a reproducible set-up, run and walk-away sample prep assistant, was used to prepare PCR reactions with the GoTaq PCR sore system II, and to compare its effectiveness versus a manually pipetted procedure.

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