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Zenix-300 (3 um, 300 Å) for mAb, ADC fragments separation with direct mass spec detection
The columns used in this application were Zenix SEC-300 (3 um, 300 Å, 7.8 x 300 mm), Zenix SEC-300 (3 um, 300 Å, 4.6 x 300 mm), Zenix-C SEC-300 (3 um, 300 Å, 4.6 x 300 mm) and Zenix-C SEC-300 (3 um, 300 Å, 2.1 x 300 mm).

MAb/ADC fragment separation after IDeS digestion
This application note shows fragment separations using Zenix SEC-300, Zenix-C SEC-300, Proteomix HIC Butyl-NP5 and Proteomix RP-1000 columns.

Intact and reduced mAb/ADC, mAb fragment separation on reversed phase chromatography
This application note shows separations of mAb/ADC and mAb using the Sepax Proteomix RP-1000. With its small particle size and short column, the Proteomix RP-1000 reversed-phase chromatography is shown to provide high throughput and fast analysis of mAb, ADC and other protein therapeutics with online mass spec determination capability.

Herceptin-lysine drug conjugate analysis Zenix-C SEC-300 vs. Tosoh TSKgel G3000SWXL
This application note shows a comparison of the Zenix-C SEC 300 and Tosoh TSKgel G3000SWXL in the analysis of a herceptin-lysine drug conjugate.