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Analysis of THC and an extended metabolite suite from oral fluid using ISOLUTE SLE+ Supported Liquid Extraction columns prior to LC-MS/MS
The method described in this application note achieves high recoveries of THC and an extended suite of common metabolites in oral fluid from Quantisal (immunalysis) oral fluid collection devices.

Extraction of THC, THCA and carboxy-THC from oral fluid by ISOLUTE SLE+ after collection with the Intercept oral fluid drug test kit prior to GC/MS analysis
An effective and efficient ISOLUTE SLE+ protocol optimized for 400 uL and 1 mL sample capacity formats is described.

Extraction of barbiturates from oral fluid using ISOLUTE SLE+ after collection with the Quantisal collection device prior to GC/MS analysis
This application note describes the extraction of butalbarbital, butabarbital, amobarbital, pentobarbital, secobarbital, hexobarbital and phenobarbital from oral fluid matrix collected using Quantisal collection devices (immunalysis).

Extraction of barbiturates from oral fluid using ISOLUTE SLE+ after collection with the Oral-Eze collection device prior to GC/MS analysis
This application note describes the extraction of butalbarbital, butabarbital, amobarbital, pentobarbital, secobarbital, hexobarbital and phenobarbital from oral fluid matrix collected using the Oral-Eze collection devices.

Extraction of amphetamines and metabolites from urine using ISOLUTE SLE+ prior to GC/MS analysis
Prior to extraction, a simple oxidation step is performed to eliminate sympathomimetic compounds such as ephedrine and pseudoephedrine so they do not interfere with quantitation of methamphetamine.