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Biotage ISOLUTE SPE columns and 96-well plates
ISOLUTE Solid Phase Extraction products are a range of leading quality SPE columns and 96-well plates, packed with a variety of ISOLUTE non-polar, mixed-mode, polar and ion exchange sorbents. Quality controlled sorbent chemistry, particle size distribution, component purity and manufacturing procedures mean that ISOLUTE SPE products perform reliably time after time. From biological fluids to wastewater samples, the wide range of sorbents and formats along with the wealth of technical and application support available from Biotage mean you can develop robust, reproducible SPE methods giving high analyte recovery and clean extracts.

Biotage ISOLUTE SLE+ Supported Liquid Extraction columns and plates
ISOLUTE SLE+ Supported Liquid Extraction plates and columns are designed to provide stress free extraction of analytes from biological fluids, with high analyte recoveries, and clean, protein and phospholipid free extracts. Methods are easy to develop, and automation is simple.

Acidic, basic and neutral drug screen of hydrolyzed urine using supported liquid extraction prior to LC-MS/MS analysis
ISOLUTE SLE+ is used to quickly screen a panel of drugs from a small amount of urine (100 uL).

Extraction of estrone and estradiol from human serum using ISOLUTE SLE+ prior to HPLC-MS/MS
This application note describes a simple supported liquid extraction method for extraction of estrone and estradiol from human serum. An analytical HPLC-MS/MS method that avoids the use of derivatization or fluoride adduct stabilization (two approaches often used to enhance method sensitivity) is used.

Extraction of illicit drugs and pesticides from liver tissue using ISOLUTE SLE+ prior to GC/MS analysis
This application note describes the extraction of a broad range of analytes from liver tissue matrix prior to GC/MS analysis using ISOLUTE SLE+ supported liquid extraction columns. A protocol has been developed that allows the simultaneous extraction of various drugs of abuse classes: amphetamines, barbiturates, benzodiazepines, cocaine, ketamine, THC.

Extraction of amphetamines and analogues from hair using ISOLUTE SLE+ prior to GC/MS analysis
This application note describes the extraction of amphetamine and amphetamine-style compounds from hair matrix prior to GC/MS analysis following bead homogenization. An effective and efficient ISOLUTE SLE+ protocol optimized for 1 mL capacity formats is detailed.

Protein and phospholipid removal products
ISOLUTE PLD+ protein and phospholipid removal plates and columns provide a very effective but extremely simple sample clean-up for LC-MS/MS analysis.

ISOLUTE PLD+ protein and phospholipid removal products – questions and answers
Here you can find useful information on the Biotage ISOLUTE PLD+ in the form of a Q&A.

How to use ISOLUTE PLD+ protein and phospholipid depletion plates
ISOLUTE PLD+ plates provide extremely efficient removal of proteins and phospholipids from blood based samples using a simple 3 step procedure.

How to use ISOLUTE PLD+ protein and phospholipid depletion columns
ISOLUTE PLD+ columns provide extremely efficient removal of proteins and phospholipids from blood based samples using a simple 3 step procedure.

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