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Extraction of tamoxifen and metabolites from urine using ISOLUTE SLE+
In this application note, Biotage demonstrates a rapid and reliable 96-well supported liquid extraction assay for the extraction of tamoxifen and metabolites from plasma.

Extraction of tamoxifen and metabolites from plasma using ISOLUTE SLE+
In this application note, Biotage demonstrates a rapid and reliable 96-well supported liquid extraction assay for the extraction of tamoxifen and metabolites from plasma.

Extraction of THC and metabolites from plasma using ISOLUTE SLE+
This application note describes the extraction of THC and its metabolites from plasma using ISOLUTE SLE+ supported liquid extraction plates followed by UPLC-MS/MS analysis.

Extraction of testosterone and other steroid hormones from human plasma using ISOLUTE SLE+ 96-well plates
The method in this application describes the use of ISOLUTE SLE+ supported liquid extraction plates (96-well) to extract a range of steroid hormones including testosterone and progesterone from human plasma. This simplified and efficient extraction method has significant analyte recoveries ranging from 90-107% with LOQs as low as 500 pg/mL.

Extraction of amphetamines from urine using ISOLUTE SLE+ 96-well plates
The method in this application describes the use of ISOLUTE SLE+ in 96 well plate format for the extraction of a range of amphetamines. This procedure is effective with sample volumes of 100 uL for analyte recoveries > 90%.

Extraction of amphetamines from urine using ISOLUTE SLE+ columns
The method in this application describes the use of ISOLUTE SLE+ in column format for the extraction of a range of amphetamines. This method is effective for sample volumes of 500 uL with analyte recoveries > 95%.

Extraction of benzodiazepines from human urine using ISOLUTE SLE+ 96-well plates and columns prior to LC-MS/MS analysis
This application note details an optimized extraction protocol for the use of ISOLUTE SLE+ supported liquid extraction plates (96-well) and 1 mL sample volume columns to extract a range of benzodiazepines from human urine.

Extraction of barbiturates from human urine using ISOLUTE SLE+ columns with GC-MS analysis
The method in this application describes the use of ISOLUTE SLE+ supported liquid extraction 1 mL sample volume columns to extract a range of barbiturates from human urine.

Effective strategies for phospholipid removal using supported liquid extraction (SLE) with LC-MS/MS analysis
This application note compares phospholipid removal using a wide variety of solvent combinations, pH control and polar extraction solvents on supported liquid extraction plates.

Concentrating a suite of semi-volatile compounds from EPA method 625 using the new Biotage TurboVap II
There are a wide range of volatile and semi-volatile contaminants finding their way into both terrestrial bodies and water sources worldwide. In the United States (US), the contaminants are analyzed according to stipulated US-EPA methods. In theEuropean Union (EU), a large number of these same compounds are tested according to the European Water Framework Directive. Though these analytes are approached differently from a regulatory perspective, it is clear that background monitoring occurs on a global basis. Initial extraction of these analytes depends on the matrix being analyzed and is often a multifaceted process, but ultimately analysts are presented with some form of extraction/organic solvent they must concentrate to achieve instrumental limits of quantification. Presented within this technical note are the results of such an evaporative process using the new Biotage TurboVap® II.

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