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Extraction of synthetic cannabinoids (SPICE) from whole blood using ISOLUTE SLE+ prior to GC-MS analysis
This application note shows an effective and efficient ISOLUTE SLE+ protocol has been developed that is optimized for extraction of 800 uL of pre-treated matrix.

Extraction of bath salts from human urine using ISOLUTE SLE+ plates prior to LC-MS/MS analysis
Analyte recoveries achieved using the method in this application note to extract baths salts from urine ranged from 87-99% with RSDs below 10% for all analytes.

Extraction of cortisol from human urine using ISOLUTE SLE+ plates prior to LC-MS/MS analysis
Analyte recoveries achieved using the method in this application note ranged from 99-101% with RSDs below 5% for all analyes.

Extraction of cortisol from human saliva using ISOLUTE SLE+ plates prior to LC-MS/MS analysis
Analyte recoveries achieved using the method in this application note ranged from 96-99% with RSDs below 3% (n=7) for all analyes.

Extraction of synthetic cannabinoids (SPICE) from oral fluid using ISOLUTE SLE+ prior to GC-MS analysis
This application note describes the extraction of a range of synthetic cannabinoids and metabolites from oral fluid collected using the Quantisal oral fluid collection device prior to GC-MS analysis.

Extraction of synthetic cannabinoids from hydrolyzed urine using ISOLUTE SLE+ prior to GC-MS analysis
Effective and efficient ISOLUTE SLE+ protocols optimized for sample loading volumes of either 400 uL or 1 mL are described in this application note.

Extraction of nicotine and metabolites from urine, serum, plasma and whole blood using ISOLUTE SLE+ prior to LC-MS/MS analysis
This application note describes a SLE protocol for the extraction of nicotine, cotinine, 3-OH-cotinine, nornicotine, norcotinine and anabasine from urine, serum, plasma and whole blood using ISOLUTE SLE+ plates with LC-MS/MS detection.

Extraction of illicit drugs from hemolyzed whole blood using ISOLUTE SLE+ columns prior to LC-MS/MS analysis
This application note describes the extraction of different drugs in hemolyzed whole blood, which are typically screened for forensic toxicology panels, using ISOLUTE SLE+ supported liquid extraction columns in the 1 mL and 2 mL sample capacity formats.

Extraction of synthetic cannabinoids (SPICE) from oral fluid using ISOLUTE SLE+ 96-well plates and columns prior to LC-MS/MS
This application note describes the extraction of a range of SPICE drugs and metabolites from neat oral fluid and oral fluid from a commercial collection kit using ISOLUTE SLE+ in both 96-well plate and column formats.

Automated extraction of synthetic cannabinoids (SPICE) from urine using ISOLUTE SLE+ prior to LC-MS/MS
This application note describes the extraction of a range of SPICE drugs and metabolites in urine which are typically screened in forensic toxicology panels using ISOLUTE SLE+ in a 96-well plate format.

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